Endometriosis Knowledgebase


A repository for genes associated with endometriosis

Results


PMID 16084898
Gene Name IL2RB
Condition Endometriosis
Association Associated
Mutation IL-2R beta-627*C homozygote, IL-12R beta 1 codon 37, IL-18 105
Sex Female
Associated genes IL-2R beta, IL-18
Other associated phenotypes Endometriosis
Interleukin-2 receptor beta (IL-2R beta)-627*C homozygote but not IL-12R beta 1 codon 378 or IL-18 105 polymorphism is associated with higher susceptibility to endometriosis.

Fertil Steril. 2005 Aug;84(2):510-2.

Hsieh, Yao-Yuan| Chang, Chi-Chen| Tsai, Fuu-Jen| Hsu, Chin-Mu| Lin, Cheng-Chieh| Tsai, Chang-Hai

Department of Obstetrics and Gynecology, China Medical University Hospital, Taichung, Taiwan.

Interleukin (IL)-2 R-627*C homozygote and C allele are related to higher susceptibility to endometriosis. Interleukin-12Rbeta1 codon 378 and IL-18 105 gene polymorphisms are not correlated with endometriosis development.

Mesh Terms: *Alleles| *Cytosine| Endometriosis/*genetics| Female| *Genetic Predisposition to Disease| *Homozygote| Humans| Interleukin-18/*genetics| Interleukin-2 Receptor beta Subunit| Polymorphism, Genetic/genetics| Receptors, Interleukin/*genetics| Rece