Results
PMID | 12906167 |
Gene Name | CDH1 |
Condition | Endometriosis |
Association |
Associated |
Population size | 62 |
Population details | 62 (32 patients with endometriosis, 30 healthy women) |
Sex | Female |
Associated genes | E-cadherin |
Other associated phenotypes |
Endometriosis |
Chin Med Sci J. 2002 Jun;17(2):121-3. Fu, Chenwei| Lang, Jinghe Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, CAMS & PUMC, Beijing 100730. OBJECTIVE: To investigate the serum sE-cadherin level in patients with endometriosis and the alterations of that level in healthy control during the menstrual cycle. METHODS: Thirty-two patients with endometriosis and 30 healthy women were tested for serum sE-cadherin levels by enzyme-linked immunosorbent assay. RESULTS: The serum sE-cadherin levels in healthy control did not vary throughout the menstrual cycle, which were lower than those in patients with endometriosis. CONCLUSIONS: E-cadherin might be involved in endometrial shedding during menstruation in endometriosis patients. The serum sE-cadherin assay might be helpful as a serum marker for the diagnosis and management of endometriosis. Mesh Terms: Adult| Cadherins/*blood| Endometriosis/*blood| Female| Humans| Menstrual Cycle|DA 2004/03/17 05:00 |