Endometriosis Knowledgebase


A repository for genes associated with endometriosis

Results


PMID 12906167
Gene Name CDH1
Condition Endometriosis
Association Associated
Population size 62
Population details 62 (32 patients with endometriosis, 30 healthy women)
Sex Female
Associated genes E-cadherin
Other associated phenotypes Endometriosis
Serum soluble E-cadherin level in patients with endometriosis.

Chin Med Sci J. 2002 Jun;17(2):121-3.

Fu, Chenwei| Lang, Jinghe

Department of Obstetrics and Gynecology, Peking Union Medical College Hospital, CAMS & PUMC, Beijing 100730.

OBJECTIVE: To investigate the serum sE-cadherin level in patients with endometriosis and the alterations of that level in healthy control during the menstrual cycle. METHODS: Thirty-two patients with endometriosis and 30 healthy women were tested for serum sE-cadherin levels by enzyme-linked immunosorbent assay. RESULTS: The serum sE-cadherin levels in healthy control did not vary throughout the menstrual cycle, which were lower than those in patients with endometriosis. CONCLUSIONS: E-cadherin might be involved in endometrial shedding during menstruation in endometriosis patients. The serum sE-cadherin assay might be helpful as a serum marker for the diagnosis and management of endometriosis.

Mesh Terms: Adult| Cadherins/*blood| Endometriosis/*blood| Female| Humans| Menstrual Cycle|DA 2004/03/17 05:00